AIDS Research Centre, National Yang-Ming University
Characterization of a GNMT gene knockout mouse model and application of the model in the hepatocarcinogenesis study.
20070501
20080415
20090205
90
30
140
20070819
20080513
20090219
070002
Shih-Feng Tsai
Division of molecular & genomic medicine, National Health Research Institutes
SNP analysis on HCC – correlation with genomic instability and gene expression
20070526
96
20070820
070003
Ya-Wen Lin
Department of Microbiology and Immunology, National Defense Medical Center
The Wnt Antagonist SFRPs Family in Hepatocarcinogenesis
20070802
90
20071018
070004
Wen-Ya Huang
Department of Medical Laboratory Science and Biotechnology, National Cheng Kung University
Application of serum of HBV carriers
20070831
20
withdraw
070005
Chi-Ling Chen
Graduate Institute of Clinical Medicine, National Taiwan University
Whole genome approach of HCC patients from multiplex family
20071018
40
20071112
070006
Sen-Yung Hsieh
Liver Research Unit, Chang Gung Memorial Hospital
Conditional onconomics of human hepatoma
20071126
20090115
36
105
20071226
20090205
080007
Hsiao-Fang Sun
Institute of Molecular Medicine, National Cheng Kung University
The Effect of Epstein-Barr Virus Infection on Genomic Alteration and Tumorigenic Susceptibility
20080313
90
20080530
080008
Shiou-Hwei Yeh
Graduate Institute of Microbiology, National Taiwan University College of Medicine
Study of the gender difference in HBV-related HCCs: synergistic carcinogenic effect of HBx and androgen signaling as a mechanism
20080313
80
20080502
080009
Chi-Ying Huang
Institute of Clinical Medicine, National Yang-Ming University
Functional genomics analysis elucidates the signaling networks of Hepatocellular carcinoma
20080415
90
20080526
080010
Ming-Whei Yu
Graduate Institute of Epidemiology, College of Public Health, National Taiwan University
Identification and characterization of candidate genes involved in the pathogenic development of HCC
20080430
40
20080603
080011
Ann-Ping Tsou
Biotechnology and Laboratory Science in Medicine, National Yang-Ming University
Identification of oncomirs that affect HCC metastasis
20080807
80
20080827
080012
Kwang-Huei Lin
Graduate Institute of Biomedical Sciences , Chang Gung University
Functional significance of Dickkopf-4 positively regulated by thyroid hormone receptor in human hepatoma cells
20081020
110
20081104
080013
Chiun Hsu
Department of Oncology, National Taiwan University Hospital
Optimizing Efficacy of Current Anti-angiogenic Therapy for Hepatocellular Carcinoma
20081208
102
20081229
090014
Jian-Wei Chen
Insitute of Biomedical Sciences, National Chung Hsing University
The role of 14-3-3 zeta protein (ywhaz) in regulating epithelial plasticity and lung adenocarcinoma cell metastasis
20090309
24
20090527
090015
Ying-Chin Ko
Division of Environmental Health and Occupational Medicine, National Health Research Institutes, Taiwan
Microarray-based copy number and expression profiling in betel related liver cancer
20090319
50
20090504
090016
Chiou-Hwa Yuh
Division of Molecular and Genomic Medicine, National Health Research Institutes
Verify the Genomic and Expression Data of HCC transgenic mouse model in human hepatocellular carcinoma
20090423
102
20090504
090017
Hsiao-Sheng Liu
Microbiology & Immunology, National Cheng Kung University
The role of miR-224 in liver cancer
20090707
25
20090727
090018
Pei-Jer Chen
Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine
The assay of tissue sections from disseminated HCC patients by immunohistochemical stain
20090707
10
20090727
090019
Chung-Ming Chang
Division of Molecular and Genomic Medicine, National Health Research Institutes
Examination of HBV spliced RNAs in HBV-related HCC samples
20090730
20
20090821
090020
Shiou-Hwei Yeh
Graduate Institute of Microbiology, National Taiwan University College of Medicine
The Role of MicroRNA Mediated Regulation of Estrogen Receptor Protein in Female Hepatocarcinogenesis
20090730
90
20090821
090021
Sen-Yung Hsieh
Liver Research Unit, Chang Gung Memorial Hospital
Conditional onconomics of human hepatoma
20091023
210
20091112
090022
Wen-Sheng Wu
Department of Medical Technology, Tzu Chi University
Signal transduction in metastasis of hepatocellular carcinoma
20091109
50
Not approved
090023
Shiou-Hwei Yeh
Graduate Institute of Microbiology, National Taiwan University College of Medicine
Vascular Differentiation during Hepatocellular Carcinoma Angiogenesis
20091211
80
20091229
090024
Dar-In Tai
Liver Research Unit, Chang Gung Memorial Hospital
Genetic factors related to hepatitis B virus replication in chronic liver diseases
20091218
100
20091229
100025
Hsiao-Sheng Liu
Microbiology & Immunology, National Cheng Kung University
The role of miR-224 in hepatoma and it’s underlying mechanism
20100111
65
20100208
100026
Yi-Ming Chen
AIDS Research Centre, National Yang-Ming University
A study on the gene regulation and protein-protein interactions of GNMT and use HCC animal model to screen drugs for liver cancer
20100115
30
20100208
100027
Shiu-Feng Huang
Division of Molecular and Genomic Medicine, National Health Research Institutes
Investigation of Carboxypeptidase E splice variant (CPE-deltaN) as a Biomarker of Hepatocellular Carcinoma Metastases/Recurrence
20100205
120
20100309
100028
Li-Tzong Chen
National Institute of Cancer Research, National Health Research Institutes, Taiwan
Study of the Taiwanese cholangiocarcinoma genomics and biomarkers
20100406
32
20100521
100029
Ya-Wen Lin
Department of Microbiology and Immunology, National Defense Medical Center
The Wnt Antagonist SFRPs Family in Hepatocarcinogenesis
20100408
30
20100617
100030
Shih-Feng Tsai
Division of molecular & genomic medicine, National Health Research Institutes
Identification of HCC Susceptibility Genes in HBV-Infected Individuals by Genome-wide Association
20100525
400
Not approved
100031
Hsiao-Fang Sun
Institute of Molecular Medicine, National Cheng Kung University
Molecular mechanism of ectopic expression of TIAM2 in the tumorigenesis of Hepatocellular carcinoma
20100713
60
20100824
100032
Sen-Yung Hsieh
Liver Research Unit, Chang Gung Memorial Hospital
Conditional onconomics of human hepatoma
20100813
60
20100913
100033
Hsiao-Sheng Liu
Microbiology & Immunology, National Cheng Kung University
The role of miR-224 in hepatoma and it’s underlying mechanism
20100820
90
20101019
100034
Jang-Yang Chang
National Institute of Cancer Research, National Health Research Institutes, Taiwan
Candidate tumor suppressor genes in HBV-infected hepatocellular carcinoma
20100825
70
20101013
100035
Chuck C.-K. Chao
Biochemistry & Molecular Biology, Chang Gung University
Primary HCC tumor samples for HURP, p53. MDM2 and Gankyrin protein levels (整合型Mechanistic study of potential factors involved in hepatocellular carcinoma子計劃二: Hepatitis B virus X target genes in modulating cell growth/ death during chemotherapy)
20100927
60
20101019
100036
Yi-Ming Chen
AIDS Research Centre, National Yang-Ming University
A study on the subclinical biomarkers in the detoxification pathway for occupational exposure-related hepatocellular carcinoma
20101027
60
Not approved
100037
Shiou-Hwei Yeh
Graduate Institute of Microbiology, National Taiwan University College of Medicine
The Role of MicroRNA Mediated Regulation of Estrogen Receptor Protein in Female Hepatocarcinogenesis
20101119
90
20101206
100038
Ya-Wen Chen
National Institute of Cancer Research, National Health Research Institutes
Characterization of p16 in tumorigenesis and metastasis: focus on mechanisms, detections and regulations
20101217
100
20110103
100039
Jia-Horng Kao
Internal medicine, National Taiwan University hospital
The impact of single nucleotide polymorphism of HLA-DP region on the development of HBV-related hepatocellular carcinoma
20101222
120
20110106
110040
Isao Matsuura
Division of Molecular and Genomic Medicine, National Health Research Institutes
Molecular Characterization of the transforming growth factor beta (TGF-b)-induced protein (TGFBi) expression in HCC
20110103
120
20110119
110041
Mi-Hua Tao
Institute of Biomedical Sciences, Academia Sinica
Generation of mouse models with chimeric human liver for hepatitis virus research
20110307
20
20110407
110042
Chien-Jen Chen
Genomics Research Center, Academia Sinica
Genetic Polymorphisms Associated with Hepatocellular Carcinoma in Chronic Hepatitis B and Hepatitis C Patients
20110309
1050
20110405
110043
Shih-Feng Tsai
Division of molecular & genomic medicine, National Health Research Institutes
Identification of HCC Susceptibility Genes in HBV-Infected Individuals by Genome-wide Association
20110315
120
20110426
110044
Yung-Ming Jeng
Department of Pathology, National Taiwan University Hospital
The analysis of genetic change of viral hepatitis-associated cholangiocarcinoma
20110620
45
20110725
110045
Guann-Yi Yu
Infectious Diseases and Vaccinology, National Health Research Institutes
Hepatitis C Virus- related hepatocellular carcinoma
20110628
20
20110817
110046
Li-Tzong Chen
National Institute of Cancer Research, National Health Research Institutes, Taiwan
Study of the Taiwanese cholangiocarcinoma genomics and biomarkers (continuation of the previous application)
20110628
90
20110817
110047
Hurng-Yi Wang
Graduate Institute of Clinical Medicine, National Taiwan University
Inferring evolutionary history of somatic mutations in hepatocellular carcinoma by phylogeographical approach
20110630
40
20110817
110048
Sen-Yung Hsieh
Liver Research Unit, Chang Gung Memorial Hospital
Identifying novel biomarkers, therapeutic targets and treatments for invasion, early recurrence and metastasis of human hepatoma
20110704
42
20110817
110049
JAW-CHING WU
Institute of Clinical Medicine, National Yang-Ming University
Elucidation of molecular mechanisms of metastasis of hepatocellular carcinoma and clinical implications: emphasis of epithelial-mesenchymal transition and cancer stem cell
20110826
100
20110919
110050
Jia-Horng Kao
Internal medicine, National Taiwan University hospital
The impact of single nucleotide polymorphism of HLA-DP region on the development of HBV-related hepatocellular carcinoma
20110830
120
20111003
110051
Shiou-Hwei Yeh
Graduate Institute of Microbiology, National Taiwan University College of Medicine
The functional role of β-catenin in postnatal liver regeneration and carcinogenesis
20110915
12
20111008
110052
Ya- Huei Huang
Department of Medical Research, Chang Gung Memorial Hospital
Identification and characterization of miRNAs aberrantly express in human hepatocellular carcinomas
20111021
100
20111129
110053
Yu-Ju Chen
Institute of Chemistry, Academia Sinica
Decipher the Altered Membrane Proteome and PTMome in Human Cancer Tissues: A Multiplex Platform for Biomarker Discovery and Validation
20111121
12
20111212
120054
Wei-Chien Huang
Graduate Institute of Cancer Biology, China Medical University
Novel roles of nuclear IKKalpha in tumor progression and metastasis
20120106
60
20120306
120055
Shiou-Hwei Yeh
Graduate Institute of Microbiology, National Taiwan University College of Medicine
Novel agents for hepatocellular carcinoma treatment and revention - targeting phosphatases and kinases
20120112
5
20120118
120056
Wen-Chun Hung
National Institute of Cancer Research, National Health Research Institutes, Taiwan
Role of MECP2 (Methyl CpG-binding protein 2) and PRMT6 (Protein arginine N-methyltransferase 6) in the pathogenesis of human hepatocellular carcinoma
20120123
110
20120315
120057
Sung-Liang Yu
Department of Laboratory Medicine and Medical Biotechnology, National Taiwan University Medical College
Study of a heat shock protein, HLJ1, in etiology for fatty liver
20120223
30
20120321
120058
Sen-Yung Hsieh
Liver Research Unit, Chang Gung Memorial Hospital
Identifying novel biomarkers, therapeutic targets and treatments for invasion, early recurrence and metastasis of human hepatoma
20120330
125
20120423
120059
Jia-Horng Kao
Internal medicine, National Taiwan University hospital
The impact of single nucleotide polymorphism of HLA-DP region on the development of HBV-related hepatocellular carcinoma
20120430
120
20120517
120060
Yi-Ming Chen
AIDS Research Centre, National Yang-Ming University
Identification of novel markers for hepatocellular carcinoma
20120514
240
20120604
120061
Guann-Yi Yu
Infectious Diseases and Vaccinology, National Health Research Institutes
Hepatitis C Virus- related hepatocellular carcinoma
20120619
300
20120717
120062
Pei-Jer Chen
Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine
Mapping Genetic Susceptibility Loci in Hepatitis B Virus-related Familial HCCs: A Genome-wide Association Study
20120706
300
20120717
120063
Yan-Hwa Wu
Institute of Biochemistry and Molecular Biology, National Yang-Ming University
Functional Roles of DDX3 on Regulating Cell Stemness and Its Impact on Hepatic Tumorigenesis
20120709
75
20120726
120064
Ching-Yao Yang
Department of Surgery, National Taiwan University hospital
Identification of histone methylation signature and elucidation of their regulation in metastasis and Sorafenib sensitivity of hepatocellular carcinoma (HCC)
20120810
100
20121008
120065
Xiao-hui Lee
Department of Life Sciences and Institute of Genome Sciences, National Yang-Ming University,
Probing ROCK I/II activation in liver carcinomas
20120827
80
20120914
120066
Jyh-Lyh Juang
Division of Molecular and Genomic Medicine, National Health Research Institutes
The correlation between alcohol consumption and expression of membrane protein in hepatocellular carcinoma
20120903
40
20121130
120067
Chau-Ting Yeh
Liver Research Center, Chang-Gung Memorial Hospital
Detection of HBV surface gene truncation mutations in HCC patients
20121009
400
20121121
120068
Chi-Ying Huang
Institute of Biiopharmaceutical Sciences, National Yang-Ming University
(1) Characterization of alternatively spliced genes in human Hepatocellular Carcinoma
(2) Using HCC tissue microarray to validate predicted biomarkers
20121012
90
20121121
120069
Chi-Ling Chen
Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University
The construction and validation of a predictive model of survival after diagnosis of hepatocellular carcinoma in Taiwan
20121023
5050
20121209
120070
Hui-Ching Wang
Institute of Molecular and Cellular Biology, National Tsing Hua University
Investigate the expression of Sgo1, HIF1α and FoxM1 in HBV-related liver and HCC
20121203
20
20121220
120071
Ih-Jen Su
National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes
The significance of viral oncoproteins and immune response in the prognosis of hepatocellular carcinoma in chronic hepatitis B patients receiving hepatectomy
20121224
200
20130118
130072
Chien-Jen Chen
Genomics Research Center, Academia Sinica
Genetic Polymorphisms Associated with Hepatocellular Carcinoma in Chronic Hepatitis B and Hepatitis C Patients
20130227
90
20130312
130073
Jia-Horng Kao
Hepatitis Research Center, National Taiwan University Hospital
The impact of single nucleotide polymorphisms of HLA-DP region on the development of HBV-related hepatocellular carcinoma
20130417
170
20130503
130074
Ta-Sen Yeh
Surgery, Chang Gung Memorial Hospital
Biosignature of hepatocellular carcinoma and cholangiocarcinoma
20130513
200
20130604
130075
Shih-Feng Tsai
Division of molecular & genomic medicine, National Health Research Institutes
Recurrent Somatic Mutations in Loss of Heterozygosity Regions of Hepatocellular Carcinoma
20130528
250
20130618
130076
Kwang-Huei Lin
Graduate Institute of Biomedical Sciences , Chang Gung University
What is the role of thyroid hormone receptors during oncogenesis?
20130531
160
20130618
130077
Pei-Jer Chen
Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine
Mapping Genetic Susceptibility Loci in Hepatitis B Virus-related Familial HCCs: An exome-capture sequencing Study
20130823
37
20130911
130078
Jeng-Jiann Chiu
Institute of Cellular and System Medicine, National Health Research Institutes
Endothelial Progenitors Promote Hepatocarcinoma Intrahepatic Metastasis through Monocyte Chemotactic Protein-1 Induction of MicroRNA-21
20131007
15
20131028
130079
Ching-Yao Yang
Department of Surgery, National Taiwan University hospital
Identification of histone methylation signature and elucidation of their regulation in metastasis and Sorafenib sensitivity of hepatocellular carcinoma (HCC)
20131007
100
20131028
130080
Yi-Ming Chen
Center for Infectious Disease and Cancer Research, Kaohsiung Medical University
Characterization of DEPDC6 and its Interactions with GNMT in the Pathogenesis of Hepatocellular Carcinoma
20131007
60
20131028
130081
Ping-Hui Tseng
Institute of Biochemistry and Molecular Biology, National Yang-Ming University
The roles of Toll-like receptors in hepatocellular carcinoma
20131104
30
20131125
130082
Jen-Liang Su
National Institute of Cancer Research, National Health Research Institutes, Taiwan
The expression level of Dicer is associated with sorafenib resistance in liver cancer
20131113
100
20140106
130083
Tsung-Hsien Chuang
Immunology Research Center, National Health Research Institutes
Molecular target in arginine metabolic pathway for cancer therapy
20131120
330
20131225
140084
Li-Tzong Chen
National Institute of Cancer Research, National Health Research Institutes, Taiwan
Study of the Taiwanese cholangiocarcinoma genomics and biomarkers (continuation of a previous application in 2011)
20140116
27
20140205
140085
Ann-Lii Cheng
Department of Oncology, National Taiwan University Hospital
The role of antiviral therapy in preventing early recurrence of hepatitis virus B related hepatocellular carcinoma after curative resection
20140603
60
20140630
140086
Chau-Ting Yeh
Liver Research Center, Chang-Gung Memorial Hospital
Detection of HBV surface gene truncation mutations in HCC patients
20140609
200
20140630
140087
Chien-Jen Chen
Genomics Research Center, Academia Sinica
Single Nucleotide Polymorphisms Associated with Hepatocellular Carcinoma Among Chronic Hepatitis B and Hepatitis C Patients
20140617
2000
20140707
140088
Chun-Jen Liu
Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine
Association of IL28B genotypes with the clinical outcomes of patients with dual chronic hepatitis B and C: A comparison among HBV/HCV dual infection, HBV mono-infection and HCV mono-infection
20140618
700
20140707
140089
Sen-Yung Hsieh
Liver Research Unit, Chang Gung Memorial Hospital
The roles and oncogenic mechanisms of RET-finger protein/TRIM27 in human hepatocellular carcinoma
20140619
50
20140707
140090
Hsiao-Fang Sun
Institute of Molecular Medicine, National Cheng Kung University
Genome Reprogramming in Cancer Cell
20140619
70
20140707
140091
Yi-Hsiang Liu
Department of Pathology, Chang Bing Show Chwan Memorial Hospital
Investigate roles of the modulation of cytoskeletons and their associated proteins playing in the tumor biology of human hepatocellular carcinoma
20140710
90
20140820
140092
Lin-Tsing Chen
Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital
Tumor Biology of Hepatocellular Carcinoma
20140919
90
20141106
140093
Yoa-Pu Hu
Department of Pharmacy, National Defense Medical Center
Function and expression of drug transporters dictate the different rosuvastatin systemic exposure between Asians and Caucasians
20140924
40
20141013
140094
Su-Fang Lin
National Institute of Cancer Research, National Health Research Institutes, Taiwan
FGFR2 gene fusion in Taiwanese intrahepatic cholangiocarcinoma tissues
20141208
90
20150106
150095
Wei-Lun Tsai
Division of Gastroenterology, Kaohsiung Veterans General Hospital
Identification of novel therapeutic targets in HCV related hepatocellular carcinoma using next generation sequencing
20150112
200
20150224
150096
I-Cheng Lee
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital
The Role Of Host Immune Regulators in the Prognosis of Hepatocellular Carcinoma
20150410
150
20150428
150097
Yun-Ru Liu
Joint Biobank, Taipei Medical University
The association analysis of a histone mRNA as a new biomarker of HCC recurrence
20150605
92
20150625
150098
Dar-In Tai
Gastroenterology and hepatology, Chang Gung Memorial Hospital
Human genetic polymorphism in therapeutic response of chronic hepatitis B
20150610
1000
20150707
150099
Yi-Hsiang Liu
Chiung-Chi Cheng
Chang Bing Show Chwan Memorial Hospital
Differential expression of the cytoskeleton proteins and the plectin in human hepatocellular carcinoma versus liver cells and in cholangicarcinoma versus bile duct epithelium
20150618
120
20150724
150100
Sen-Yung Hsieh
Chang Gung Memorial Hospital
In vivo functional genomics to decipher the genes/mechanisms orchestrating hepatoma invasion
20150710
180
20150803
150101
Hsu Shih-Hsien
KMU
To explore the regulatory effect of aryl hydrocarbon receptor (AhR) on initiation and enhance role of oncoprotein ISX in human hepatocellular carcinoma (HCC)
20150805
200
20150901
150102
Pei-Jer Chen
Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine
Development of new treatment and biomarker for hepatocellular carcinoma: from woodchuck to human (3/3)
20150826
120
20150916
150103
Wan-long Chuang
Kaohsiung Medical University
Chung-Ho Memorial Hospital
HCV infection affects on growth hormone signaling pathway in liver diseases and hepatocellular carcinoma progression
20150908
200
20151028
150104
Yi-Hsiang Huang
Taipei Veterans General Hospital
Division of Gastroenterology, Department of Medicine
The Role of Tid1 Expression in Behavior and Prognosis of hepatocellular Carcinoma
20150926
200
20151109
150105
Chiun Hsu
National Taiwan University Hospital
Incorporation of genomic and immunological studies for biomarker identification for hepatocellular carcinoma
20151101
600
20151126
150106
Yuh-Shan Jou
Institute of Biomedical Sciences ,Academia Sinica
Dissecting molecular mechanisms of PSPC1 overexpression driven cancer EMT, stemness and tumor metastasis.
20151230
200
20160118
150107
Pei-Jer Chen
Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine
Development of new treatment and biomarker for hepatocellular carcinoma: from woodchuck to human (3/3)
20151230
120
20160110
160108
Jui-Hsiang Hung
Department of Biotechnology, Chia Nan University of Pharmacy and Science
To investigate the effect of nucleobindin-2 overexpression by endoplasmic reticulum stress on hepatocellular carcinoma treatment
20160219
120
20160321
160109
Kwang-Huei Lin
Graduate Institutes of Biomedical Sciences, Chang Gung University
Characterization the physiological significance of angiogenesis associated gene regulated thyroid hormone
20160322
160
20160418
160110
Shih-Feng Tsai
Institute of Molecular and Genomic Medicine, National Health Research Institutes
Translational research on genomic variations in liver cancer
20160328
250
20160411
160111
I-Cheng Lee
Division of Gastroenterology and Hepatology, Department of Medicine ,Taipei Veterans General Hospital
The Role of Host Immune Regulators and Tumor Microenvironment in the Prognosis of Hepatocellular Carcinoma
20160411
200
20160615
160112
Alice L. Yu
Institute of Stem Cell and Translational Cancer Research, Linkou Chang Gung Memorial Hospital
Tumor Biology of Hepatocellular carcinoma
20160503
90
20160524
160113
Yu-Tsung Shih
Institute of Cellular and System medicine, National Health Research Institutes
Unrevealing the Metabolic Abnormalities of Endothelial Cells in Response to the Angiogenic Niche Composed by Endothelial Progenitors and Hepatocarcinoma Cells
20160524
24
20160627
160114
Shiou-Hwei Yeh
Dept. of Microbiology, College of Medicine, National Taiwan University
The distribution trend of Glypican-3 expression in hepatocellular carcinoma
20160817
120
20160906
160115
Li Ching Li
Shuang Ho Hospital, Taipei Medical University
Investigation of nicotine/cigarette-smoke promotes metastasis of hepatocellular carcinoma through nAChR and pre-clinically evaluation of correlation between smoking and hepatocellular carcinoma
20161011
180
20161128
160116
Chiun Hsu
National Taiwan University Hospital
Incorporation of genomic and immunological studies for biomarker identification for hepatocellular carcinoma
20161026
800
20161128
160117
Hsieh, Shie-Liang
Genomics Research Center, Academia Sinica
Liver and plasma C-type lectin 18 (CLEC18) expression in hepatitis B and C virus infected patients
20161122
260
20170209
160118
Yan-Hwa Wu Lee
Department of Biological Science and Technology, National Chiao-Tung University
Functional roles of DDX3 in regulating exosome biogenesis and its therapeutic potential on hepatic tumorigenesis
20161214
75
20170811
170119
Yi-mimg Chen
Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University
A study of the epigenetic regulation of GNMT gene expression and the role GNMT plays in the control of global DNA methylation
20170127
80
20170209
170120
Pei-Jer Chen
Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University
Taiwan Research Biosignature Network on Patients at High Risk of Hepatocellular Carcinoma (TARGET-HCC)
20170213
90
20170419
170121
Hsien-Chung Yu
Division of Gastroenterology and Hepatobiliary, Department of Internal Medicine, Kaohsiung Veterans General Hospital
The correlation between serum BioFibroScore, Pre-S Deletion and Histological Fibrosis in Chronic Hepatitis B Patients with Hepatocellular Carcinoma Receiving Curative Resection
20170214
150
20170419
170122
Tung-Hung Su
Internal Medicine, National Taiwan University Hospital
Clinical implications of immunophenotypes in liver fibrosis and hepatocellular carcinoma
20170301
150
20170612
170123
Chia-Hung Yen
Graduate Institute of Natural Products, Kaohsiung Medical University
A study of the role of redox state in the development of sarcomatoid hepatocellular carcinoma and its application in anti-liver cancer drug discovery.
20170519
120
20171020
170124
Chau-Ting Yeh
Liver Research Center, Chang-Gung Memorial Hospital
Clinical and molecular characterization of hepatocellular carcinoma carrying distinct patterns of HBV S gene truncation mutations
20170324
11
20170612
170125
Chau-Ting Yeh
Liver Research Center, Chang-Gung Memorial Hospital
Clinical and molecular characterization of hepatocellular carcinoma carrying distinct patterns of HBV S gene truncation mutations
20170624
200
20170811
170126
Jun-Yang Liou
Institute of Cellular and System Medicine, National Health Research Institutes
To investigate the role of AKR1B10 expression and metabolism in regulating epithelial-mesenchymal transition and drug resistance of hepatocellular carcinoma
20170928
150
20171222
170127
Li-Fen Shen
Drug Development Division, TaiRx, Inc.
A Pilot Study of Tumor Prognostic Biomarker in Hepatocellular Carcinoma
20171212
140
20180205
170128
Jun-Yang Liou
Institute of Cellular and System Medicine, National Health Research Institutes
To investigate the role of AKR1B10 expression and metabolism in regulating epithelial-mesenchymal transition and drug resistance of hepatocellular carcinoma
20171228
150
20180205
180129
Yue-Liang Guo
National Institute of Environmental Health Sciences, National Health Research Institute
Air pollutants and hepatocellular carcinoma survival
20180131
1000
20180927
180130
Jyh-Lyh Juang
Institute of Molecular and Genomic Medicine, National Health Research Institutes
Identification of potential mechanism for liver cancer in tumor tissue
20180207
40
20180409
180131
Mei-Hwei Chang
Pediatrics, National Taiwan University College of Medicine
Long-term Follow-up of Chronic Hepatitis B Virus Infection from Mother-to-Infant Transmission to Adult Life
20180319
50
20180409
180132
Jinn-Moon Yang
Institute of Bioinformatics and System Biology, National Chiao Tung University
Intelligent Computing Precision Medical and Drug Development Platform – Integrated dynamic systems biology models to study the mechanisms between diabetes mellitus and liver cancer for developing biomarkers and drugs
20180321
120
20180409
180133
Jui-Hsiang Hung
Department of Biotechnology, Chia Nan University of Pharmacy and Science
To investigate the mechanism of endoplasmic reticulum stress-induced nucleobindin-2 expression and its effect on the treatment of liver cancer
20180322
120
20180626
180134
Yan-Hwa Wu Lee
Department of Biological Science and Technology, National Chiao Tung University
Center for Intelligent Drug Systems and Smart Bio-devices, IDS2B
20180330
30
20180409
180135
Pei-Jer Chen
Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University
Taiwan Research Biosignature Network on Patients at High Risk of Hepatocellular Carcinoma (TARGET-HCC)
20180427
50
20180626
180136
Kun-Chih Tsai
National Institute of Cancer
Research, National Health Research Institutes
The role of ASPM-Wnt signaling in hepatoma cancer stemness and progression and the development of the related nano- and gene therapy
20180821
70
Overdue
180137
Jyh-Lyh Juang
Institute of Molecular and Genomic Medicine, National Health Research Institutes
Identification of potential mechanism for liver cancer in tumor tissue
20181003
40
20181220
180138
Mei-Hwei Chang
Pediatrics, National Taiwan University College of Medicine
Long-term Follow-up of Chronic Hepatitis B Virus Infection from Mother-to-Infant Transmission to Adult Life
20181005
150
20181220
180139
Tzu-Ling Tseng
Bio Preventive Medicine Corp.
Cancer biomarkers development
20181012
60
20190227
180140
Chi-Ying Huang
Institute of Biopharmaceutical Sciences, National Yang-Ming University
The prognostic correlation of exosomal GPC3 level at diagnosis, surveillance and survival of patients with hepatocellular carcinoma
20181105
50
20190227
180141
Wen-Lung Ma
Graduate Institute of BioMedical Sciences, China medical university
Study of the metabolic syndrome-related VLDL and VLDLR roles in hepatocellular carcinoma
20181112
225
20181220
190142
Chao-Wei Hsu
Division of Gastroenterology and Hepatology, Chang-Gung Memorial Hospital
Clinical and Functional Significance of Infections of Genetically Different Hepatitis Delta Virus
20190108
300
20190227
190143
Mei-Hwei Chang
Pediatrics, National Taiwan University College of Medicine
Long-term Follow-up of Chronic Hepatitis B Virus Infection from Mother-to-Infant Transmission to Adult Life
20190111
100
20190227
190144
Yan-Hwa Wu Lee
Department of Biological Science and Technology, National Chiao Tung University
Center for Intelligent Drug Systems and Smart Bio-devices, IDS2B
20190314
50
20190424
190145
Ting-Fen Tsai
Department of Life Sciences and Institute of Genome Sciences, National Yang-Ming University
Development of novel therapeutics for non-alcoholic fatty liver diseases (NAFLD) and steatohepatitis (NASH)
20190322
260
20190820
190146
Shih-Feng Tsai
Institute of Molecular and Genomic Medicine, National Health Research Institutes
Translational research on genomic variations in liver cancer
20190327
150
20190424
190147
Ling-Yueh Hu
Laboratory of Translational Medicine Office, Development Center for Biotechnology
Explore the expression and distribution of the immune checkpoint related proteins in normal liver tissue
To Study the Association between Mutational Spectrum/Tumor Microenvironment and Prognosis in HCC/CC Using Archived Specimens
20190520
300
20190625
190149
Yang-Hsiang Lin
Liver Research Center, Chang Gung Memorial Hospital, Linkou
Characterization of LOC731656 functions in human hepatocellular carcinoma and its clinical significance
20190702
80
20190820
190150
Lee, Mei-Hsuan
Institute of Clinical Medicine, National Yang Ming University
DNA methylation profiling, antigen representation of HLA and associated risk for hepatocellular carcinoma
20190815
900
20191007
190151
Sen-Yung Hsieh
Dept. of Gastroenterology & Hepatology, Linkou Chang Gung Memorial Hospital
Decipher genomic and epigenomic alternations in the liver and digestive cancers
20190909
108
20191007
190152
Oliver Yoa-Pu Hu
Collage of Pharmacy, Taipei Medical University
Study of drug metabolism in homogenized liver
20191015
10
Overdue
190153
Yan-Hwa Wu Lee
Department of Biological Science and Technology, National Chiao Tung University
Center for Intelligent Drug Systems and Smart Bio-devices, IDS2B
20191015
30
20191213
190154
JAW-CHING WU
Institute of Clinical Medicine, National Yang Ming University
Investigating the regulatory mechanism of glycosphingolipids in Hepatitis B virus-transgenic mice and human liver cancer specimens for the development of novel diagnostic and therapeutic strategies for Hepatocellular carcinoma
20191115
680
20200213
190155
Sheng-Hui Lan
Department of Life Sciences
and Institute of Genome Sciences, National Yang-Ming University
Physiologic and pathologic roles of FUS for microRNA turnover by selective autophagy
20191129
16
20200213
200156
Jun-Yang Liou
Institute of Cellular and System Medicine, National Health Research Institutes
Characterization of HIOMT isoform for 5-MTP biosynthesis and its defect in cancer
20200225
150
20200422
200157
Chao-Wei Hsu
Division of Gastroenterology and Hepatology, Chang-Gung Memorial Hospital
Clinical and Functional Significance of Infections of Genetically Different Hepatitis Delta Virus
20200323
8
20200422
200158
Chen, Shao-Yuan
Laboratory of Translational Medicine Office, Development Center for Biotechnology
Explore the impact of signal transduction factors in tumor progression
20020417
90
20200714
200159
Pei-Ing Hwang
Digital Health Planning Group, Development Center for Biotechnology
Development of Biomarkers for Precision Medicine with Big Data Analyses
20200602
50
20200812
200160
Cheng-Yi Chen
Department of Cell Biology and Anatomy, National Cheng Kung University
Department of Biological Science and Technology, National Chiao Tung University
Center for Intelligent Drug Systems and Smart Bio-devices, IDS2B
20200827
50
20200921
200162
Shun-Fa Yang
Department of Medical Research, Chung Shan Medical University Hospital
Study of the LncRNA genetic variants in hepatocellular carcinoma
20200309
400
20200422
200163
Ho Ming-Chih
Surgery, National Taiwan University Hospital
Specific HBV-human chimera DNA as a novel biomarker for predicting the outcome of HCC after transplantation (2)
20200409
34
20200520
200164
Chao-Cheng Huang
Pathology, Kaoshiung Chang Gung Memorial Hospital
Investigating the Role of Delta-like 1 Homolog (DLK1) in T Cell Immune Surveillance of Hepatocellular Carcinoma
20200408
80
20200520
200165
Kuo-Shyang Jeng
General Surgery, Far Eastern Memorial Hospital
To investigate the role of inhibition of sonic Hedgehog signaling pathway in increasing the sensitivity of doxorubicin in hepatocellular carcinoma-an in vitro and in vivo study
20200413
20
20200520
200166
Lin Ming-Tsung
Division of Hepato-Gastroenterology, Kaohsiung Chang Gung Memorial Hospital
Biomarkers analysis for hepatocellular carcinoma and liver fibrosis
20200408
20
20200520
200167
Kelvin Kun-chih Tsai
Graduate institute of Clinical Medicine, Taipei Medical University
The role of ASPM-Wnt signaling in hepatoma cancer stemness and
progression and the development of the related nano- and gene-therapy
20200416
90
20200610
200168
Chen Yaw-Sen
Department of Surgery, E-Da Hospital
To study amino-acid-dependent GATORC1/mTORC1 signaling in the development of hepatocellular carcinoma
20200423
90
20200610
200169
Hsieh, Ching-Hua
Plastic Surgery, Kaohsiung Chang Gung Memorial Hospital
Using circulating biomarkers to identify the patients with hepatocellular carcinoma-based on the samples from National Biobank Consortium of Taiwan
20200414
50
20200714
200170
Chih-Yang Huang
Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Study the genes and molecular mechanisms affecting of colorectal cancer, lung cancer and liver cancer
20200512
23
20200812
200171
Wen-Chi, Yang
Hematology and medical oncology, E-Da hospital
Immune landmark in local limited HCC and advanced HCC
20200422
120
20200921
200172
Jyh-Lyh Juang
Institute of Molecular and Genomic Medicine, National Health Research Institutes
Indentification of potential mechanism for liver cancer in tumor tissue
20200922
48
20201028
200173
Zhong-Zhe Lin
Medical Oncology, National Taiwan University Cancer Center
Define the clinicopathologic significance of CpG island methylator phenotype in intrahepatic cholangiocarcinoma
20201111
100
20201127
210174
Andrew Yueh
Institute of biotechnology and pharmaceutical research, National Health Research Institute
Development of next-generation biologics for cancer & immunotherapy therapy
Item 1. Development of next-generation antibody drug conjugates
20210114
40
20210222
210175
Yi-Ming Arthur Chen
Graduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University
Using TLCN unlink samples to evaluate the application of novel circulating microRNAs on hepatocellular carcinoma diagnostic and prognostic
20210412
100
20210625
210176
Ruey-Hwa Chen
Institute of Biomedical Science, Academia Sinica
The roles of long noncoding RNA LINAT in tumor progression
20210930
100
20211007
210177
Kwang-Huei Lin
Graduate Institutes of Biomedical Sciences, Chang-Gung University
The clinical significance of thyroid hormone-regulated non-coding RNAs
20211027
120
20211217
220178
Yi-Hsin Yang
Institute of cancer research, National Health Research Institute
Investigate metabolic complications in liver cancer patients treated with target therapies
20220117
6000
20220223
220179
Yi-Wen Huang
CRC, Taipei Medical University Hospital
To explore the difference in molecular signature between virus and steatosis-related liver cancer
20220510
1050
20220718
220180
Mei-Hsuan Lee
Institute of Clinical Medicine, National Yang Ming Chiao Tung University
Genetic susceptibility and the associated risk of cholangiocarcinoma and non-hepatitis B and non-hepatitis C hepatocellular carcinoma
20220617
300
20220718
220181
Tsai-Yuan Hsieh
Division of Gastroenterology, Tri-Service General Hospital
To investigate the regulatory mechanisms of CRNDE gene in hepatocellular carcinoma and the clinical significance of its associated molecular expression
20220717
50
20220831
220182
Shu-Chi Wang
Department of Medical Laboratory Science and Biotechnology, Kaohsiung Medical University
Investigation of exosomal DANCR in predicting of HCC recurrence in HCV-related HCC post curative therapy, mechanism of action, and the feasibility on precision medicine application.
20220812
200
20220831
220183
Shao-Chun Wang
College of Medicine, China Medical University & Hospital
Developing novel tumor and blood biomarkers of marker-guided effective cancer therapies
20220726
108
20220831
220184
Chao-Wei Hsu
Department of Hepatology and Gastroenterology, Chang Gung Memorial Hospital
Analyses of Hepatitis Delta Virus Mutants Isolated from Hepatocellular Carcinoma Patients Co-infected with Hepatitis B/D Viruses
20220815
4
20220831
220185
Hsin-Ling Hsu
Institute of Molecular and Genomic Medicine, National Health Research Institutes
Roles of microRNA-34a and MCT-1 in lipid metabolism during macrophage reprogramming and carcinogenesis
20220926
28
20230316
220186
Donching Lee
TAQKEY Science Co., Ltd.
DNA methylation for hepatocellular carcinoma
20221008
15
20230107
220187
Pei-Jer Chen
Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine
Contribution of HDV in HBV-induced insertional mutagenesis in HBV, HDV-related HCC
20221014
70
20221216
220188
Cherng Yih-Giun
Superintendent Office, Taipei Medical University-Shuang Ho Hospital, Ministry of Health and Welfare
Identification of Targetable mediators involving in PP1R15B Pathway to Overcome Resistance to Lenvatinib in Drug-Tolerant Persister Liver Cancer
20221109
30
20230321
220189
Chau-Ting Yeh
School of medicine, Chang-Gung University
Analysis of the role of ApoC1 in hepatocarcinogenesis
20221115
200
20221216
220190
Jo Ting Tsai
Radiation Oncology, Taipei Medical University-Shuang Ho Hospital, Ministry of Health and Welfare
A Mechanism Study of the Interplay between pre-mRNA-SRSF1 and XIRP2 in Radiation Resistance and Metastasis of Hepatocellular Carcinoma
20221118
30
20230328
220191
Hui-Lin Wu
Hepatitis Research Center, National Taiwan University Hospital
Study on the early recurrence of HBV-associated hepatocellular carcinoma: with emphasis on the molecular mechanisms and clinical implications of a novel metastatic tumor antigen 1 spliced variant, MTA1dE4
20221227
150
20230222
230192
En-Chi Hsu
Institute of Molecular and Genomic Medicine, National Health Research Institutes
Develop Liquid Biopsy-Based Exosomal Correlative Signature Utilizing Oncoprotein-microRNA-circRNA Functional Networks for Early Detection of Liver Cancer
20230105
150
20230406
230193
Chao-Wei Hsu
Department of Hepatology and Gastroenterology, Chang Gung Memorial Hospital
Analyses of Hepatitis Delta Virus Mutants Isolated from Hepatocellular Carcinoma Patients Co-infected with Hepatitis B/D Viruses
20230109
70
20230222
230194
Jer-Wei Chang
Precision Medicine and Informatics, Institute Drug Evaluation Platform, Development Center for Biotechnology
Development of Different Cancers Biomarkers for Precision Medicine with Big Data Analyses
20230203
15
20230628
230195
Tang- Yuan Chu
Department of Obstetric & Gynecology, Tzu Chi Hospital, Hualien
FE25 cell transformation as a serum bioassay to detect cancers and estimate tumor load: a validation study and characterization of the transformation activity
20230602
32
20230822
230196
Hung-Chih Yang
Graduate Institute of Microbiology, NTUCM
Comprehensive Delineation of Oncofetal Ecosystem in Hepatocellular Carcinoma after Hepatectomy
20230620
270
20230822
230197
Wen-Hui Su
Department of Biomedical Sciences, Chang Gung University
Feasibility Assessment of Polygenic Risk Score-Stratified Screening in Hepatocellular Carcinoma.
20230911
600
20231026
230198
Kun-Yu Lai
Department of Optics and Photonics, National Central University
High throughput Raman spectroscopy: A new DNA testing for cancers and cord blood
20231026
10
20231213
230199
Kuei-Yen Tsai
Division of General
Surgery, Department of
Surgery, Taipei Medical
University-Shuang
Ho Hospital
Investigate the mechanism of non-coding RNA LINC00885 in promoting nonalcoholic fatty liver disease
